@prefix bemo: .
@prefix bfo: .
@prefix dcterms: .
@prefix iao: .
@prefix obo: .
@prefix oboInOwl: .
@prefix owl: .
@prefix prov: .
@prefix rdfs: .
@prefix skos: .
@prefix xsd: .
bemo:BEMO_0000002 a owl:Class ;
rdfs:label "metric pillar"@en ;
iao:0000115 "A high-level organizational class grouping biomedical evidence metrics by scientific function."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000002" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000003 a owl:Class ;
rdfs:label "metric category"@en ;
iao:0000115 "A source-preserving organizational class grouping biomedical evidence metrics within a metric pillar."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000003" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000101 a owl:Class ;
rdfs:label "metric input specification"@en ;
iao:0000115 "An information content entity specifying a required or optional input role for a metric computation."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000101" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000102 a owl:Class ;
rdfs:label "metric output specification"@en ;
iao:0000115 "An information content entity specifying the datatype, scale, unit, range, and interpretation of a metric output."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000102" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000103 a owl:Class ;
rdfs:label "metric applicability profile"@en ;
iao:0000115 "An information content entity specifying evidence levels, study types, domains, and contexts to which a metric applies."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000103" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000104 a owl:Class ;
rdfs:label "metric validation record"@en ;
iao:0000115 "An information content entity documenting validation design, benchmark, results, scope, and status for a metric or computation profile."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000104" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000105 a owl:Class ;
rdfs:label "metric governance record"@en ;
iao:0000115 "An information content entity documenting ownership, review, approval, lifecycle, version, and change history."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000105" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000106 a owl:Class ;
rdfs:label "uncertainty specification"@en ;
iao:0000115 "An information content entity specifying how uncertainty is estimated, propagated, calibrated, and reported."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000106" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000202 a owl:Class ;
rdfs:label "scientific claim"@en ;
iao:0000115 "An information content entity asserting a biomedical proposition that may be evaluated using evidence metrics."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000202" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000203 a owl:Class ;
rdfs:label "body of evidence"@en ;
iao:0000115 "A defined collection of evidence records assembled to evaluate one or more biomedical claims."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000203" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000300 a owl:Class ;
rdfs:label "metric computation process"@en ;
iao:0000115 "A process that applies a metric computation specification to validated inputs and produces a metric assessment."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000300" ;
rdfs:subClassOf bfo:0000015 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_3000002 a owl:ObjectProperty ;
rdfs:label "uses metric"@en ;
iao:0000115 "Connects a metric assessment to the metric used."@en ;
oboInOwl:id "BEMO:3000002" ;
rdfs:domain bemo:BEMO_0000200 ;
rdfs:range bemo:BEMO_0000001 .
bemo:BEMO_3000003 a owl:ObjectProperty ;
rdfs:label "assesses evidence object"@en ;
iao:0000115 "Connects a metric assessment to the evidence object assessed."@en ;
oboInOwl:id "BEMO:3000003" ;
rdfs:domain bemo:BEMO_0000200 ;
rdfs:range bemo:BEMO_0000201 .
bemo:BEMO_3000004 a owl:ObjectProperty ;
rdfs:label "has required input specification"@en ;
iao:0000115 "Connects a computation specification to a required input specification."@en ;
oboInOwl:id "BEMO:3000004" .
bemo:BEMO_3000005 a owl:ObjectProperty ;
rdfs:label "has optional input specification"@en ;
iao:0000115 "Connects a computation specification to an optional input specification."@en ;
oboInOwl:id "BEMO:3000005" .
bemo:BEMO_3000006 a owl:ObjectProperty ;
rdfs:label "has output specification"@en ;
iao:0000115 "Connects a computation specification to its output specification."@en ;
oboInOwl:id "BEMO:3000006" .
bemo:BEMO_3000007 a owl:ObjectProperty ;
rdfs:label "has scale type"@en ;
iao:0000115 "Connects a computation specification to a controlled scale type."@en ;
oboInOwl:id "BEMO:3000007" .
bemo:BEMO_3000008 a owl:ObjectProperty ;
rdfs:label "has computation mode"@en ;
iao:0000115 "Connects a computation specification to a computation-mode category."@en ;
oboInOwl:id "BEMO:3000008" .
bemo:BEMO_3000009 a owl:ObjectProperty ;
rdfs:label "has computation readiness status"@en ;
iao:0000115 "Connects a computation specification to its readiness status."@en ;
oboInOwl:id "BEMO:3000009" .
bemo:BEMO_3000010 a owl:ObjectProperty ;
rdfs:label "has formula status"@en ;
iao:0000115 "Connects a computation specification to formula availability status."@en ;
oboInOwl:id "BEMO:3000010" .
bemo:BEMO_3000011 a owl:ObjectProperty ;
rdfs:label "has directionality"@en ;
iao:0000115 "Connects a computation specification to interpretation directionality."@en ;
oboInOwl:id "BEMO:3000011" .
bemo:BEMO_3000012 a owl:ObjectProperty ;
rdfs:label "has uncertainty specification"@en ;
iao:0000115 "Connects a computation specification or assessment to an uncertainty specification."@en ;
oboInOwl:id "BEMO:3000012" .
bemo:BEMO_3000013 a owl:ObjectProperty ;
rdfs:label "has applicability profile"@en ;
iao:0000115 "Connects a metric to an applicability profile."@en ;
oboInOwl:id "BEMO:3000013" .
bemo:BEMO_3000014 a owl:ObjectProperty ;
rdfs:label "has validation record"@en ;
iao:0000115 "Connects a metric or computation profile to a validation record."@en ;
oboInOwl:id "BEMO:3000014" .
bemo:BEMO_3000015 a owl:ObjectProperty ;
rdfs:label "has governance record"@en ;
iao:0000115 "Connects an ontology entity to its governance record."@en ;
oboInOwl:id "BEMO:3000015" .
bemo:BEMO_3000016 a owl:ObjectProperty ;
rdfs:label "depends on metric"@en ;
iao:0000115 "Represents a curated computational dependency between metrics."@en ;
oboInOwl:id "BEMO:3000016" .
bemo:BEMO_3000017 a owl:ObjectProperty ;
rdfs:label "derived from metric"@en ;
iao:0000115 "Represents a curated derivation relation between metrics."@en ;
oboInOwl:id "BEMO:3000017" .
bemo:BEMO_3000018 a owl:ObjectProperty ;
rdfs:label "composite of metric"@en ;
iao:0000115 "Connects a composite metric to a component metric."@en ;
oboInOwl:id "BEMO:3000018" .
bemo:BEMO_3000019 a owl:ObjectProperty ;
rdfs:label "validated against"@en ;
iao:0000115 "Connects a metric profile or assessment to a benchmark or reference standard."@en ;
oboInOwl:id "BEMO:3000019" .
bemo:BEMO_3000020 a owl:ObjectProperty ;
rdfs:label "generated by computation process"@en ;
iao:0000115 "Connects a metric assessment to the process that generated it."@en ;
oboInOwl:id "BEMO:3000020" ;
owl:equivalentProperty prov:wasGeneratedBy ;
skos:closeMatch .
bemo:BEMO_3100001 a owl:DatatypeProperty ;
rdfs:label "metric identifier"@en ;
iao:0000115 "Stable OBO-style CURIE assigned to a metric."@en ;
oboInOwl:id "BEMO:3100001" ;
rdfs:range xsd:string .
bemo:BEMO_3100002 a owl:DatatypeProperty ;
rdfs:label "profile version"@en ;
iao:0000115 "Version of a computation profile."@en ;
oboInOwl:id "BEMO:3100002" .
bemo:BEMO_3100003 a owl:DatatypeProperty ;
rdfs:label "human-readable formula"@en ;
iao:0000115 "Human-readable formula or protocol requirement."@en ;
oboInOwl:id "BEMO:3100003" .
bemo:BEMO_3100004 a owl:DatatypeProperty ;
rdfs:label "machine formula language"@en ;
iao:0000115 "Language used for a machine-readable formula."@en ;
oboInOwl:id "BEMO:3100004" .
bemo:BEMO_3100005 a owl:DatatypeProperty ;
rdfs:label "machine formula expression"@en ;
iao:0000115 "Serialized machine-readable computation expression."@en ;
oboInOwl:id "BEMO:3100005" .
bemo:BEMO_3100006 a owl:DatatypeProperty ;
rdfs:label "required inputs text"@en ;
iao:0000115 "Semicolon-delimited required input roles."@en ;
oboInOwl:id "BEMO:3100006" .
bemo:BEMO_3100007 a owl:DatatypeProperty ;
rdfs:label "optional inputs text"@en ;
iao:0000115 "Semicolon-delimited optional input roles."@en ;
oboInOwl:id "BEMO:3100007" .
bemo:BEMO_3100008 a owl:DatatypeProperty ;
rdfs:label "output datatype"@en ;
iao:0000115 "Expected output datatype."@en ;
oboInOwl:id "BEMO:3100008" .
bemo:BEMO_3100009 a owl:DatatypeProperty ;
rdfs:label "unit text"@en ;
iao:0000115 "Human-readable unit or scale."@en ;
oboInOwl:id "BEMO:3100009" .
bemo:BEMO_3100010 a owl:DatatypeProperty ;
rdfs:label "minimum value"@en ;
iao:0000115 "Minimum allowed or expected numeric value."@en ;
oboInOwl:id "BEMO:3100010" .
bemo:BEMO_3100011 a owl:DatatypeProperty ;
rdfs:label "maximum value"@en ;
iao:0000115 "Maximum allowed or expected numeric value."@en ;
oboInOwl:id "BEMO:3100011" .
bemo:BEMO_3100012 a owl:DatatypeProperty ;
rdfs:label "null value"@en ;
iao:0000115 "Scientifically meaningful null value."@en ;
oboInOwl:id "BEMO:3100012" .
bemo:BEMO_3100013 a owl:DatatypeProperty ;
rdfs:label "aggregation rule"@en ;
iao:0000115 "Aggregation rule for multi-input or composite computations."@en ;
oboInOwl:id "BEMO:3100013" .
bemo:BEMO_3100014 a owl:DatatypeProperty ;
rdfs:label "normalization method"@en ;
iao:0000115 "Normalization method and version."@en ;
oboInOwl:id "BEMO:3100014" .
bemo:BEMO_3100015 a owl:DatatypeProperty ;
rdfs:label "missing data policy"@en ;
iao:0000115 "Required missing-data handling policy."@en ;
oboInOwl:id "BEMO:3100015" .
bemo:BEMO_3100016 a owl:DatatypeProperty ;
rdfs:label "uncertainty required"@en ;
iao:0000115 "Whether uncertainty reporting is mandatory."@en ;
oboInOwl:id "BEMO:3100016" ;
rdfs:range xsd:boolean .
bemo:BEMO_3100017 a owl:DatatypeProperty ;
rdfs:label "uncertainty method"@en ;
iao:0000115 "Acceptable uncertainty estimation method."@en ;
oboInOwl:id "BEMO:3100017" .
bemo:BEMO_3100018 a owl:DatatypeProperty ;
rdfs:label "confidence interval required"@en ;
iao:0000115 "Whether interval estimation is required."@en ;
oboInOwl:id "BEMO:3100018" ;
rdfs:range xsd:boolean .
bemo:BEMO_3100019 a owl:DatatypeProperty ;
rdfs:label "threshold policy"@en ;
iao:0000115 "Policy governing thresholds."@en ;
oboInOwl:id "BEMO:3100019" .
bemo:BEMO_3100020 a owl:DatatypeProperty ;
rdfs:label "quality control requirements"@en ;
iao:0000115 "Quality-control requirements for computation."@en ;
oboInOwl:id "BEMO:3100020" .
bemo:BEMO_3100021 a owl:DatatypeProperty ;
rdfs:label "calibration requirement"@en ;
iao:0000115 "Calibration requirement for the output."@en ;
oboInOwl:id "BEMO:3100021" .
bemo:BEMO_3100022 a owl:DatatypeProperty ;
rdfs:label "source row"@en ;
iao:0000115 "One-based row number in the source worksheet."@en ;
oboInOwl:id "BEMO:3100022" ;
rdfs:range xsd:integer .
bemo:BEMO_3100023 a owl:DatatypeProperty ;
rdfs:label "source record hash"@en ;
iao:0000115 "SHA-256 hash of the canonical source record."@en ;
oboInOwl:id "BEMO:3100023" ;
rdfs:range xsd:string .
bemo:BEMO_3100024 a owl:DatatypeProperty ;
rdfs:label "scientific importance score"@en ;
iao:0000115 "Source-provided scientific importance score."@en ;
oboInOwl:id "BEMO:3100024" .
bemo:BEMO_3100025 a owl:DatatypeProperty ;
rdfs:label "metric value lexical form"@en ;
iao:0000115 "Lexical representation of a metric assessment value."@en ;
oboInOwl:id "BEMO:3100025" .
bemo:BEMO_3100026 a owl:DatatypeProperty ;
rdfs:label "numeric metric value"@en ;
iao:0000115 "Numeric metric assessment value."@en ;
oboInOwl:id "BEMO:3100026" .
bemo:BEMO_3100027 a owl:DatatypeProperty ;
rdfs:label "assessment timestamp"@en ;
iao:0000115 "Time at which an assessment was generated."@en ;
oboInOwl:id "BEMO:3100027" .
bemo:BEMO_3100028 a owl:DatatypeProperty ;
rdfs:label "computation protocol version"@en ;
iao:0000115 "Version of the executed protocol."@en ;
oboInOwl:id "BEMO:3100028" .
bemo:BEMO_3100029 a owl:DatatypeProperty ;
rdfs:label "evidence snapshot identifier"@en ;
iao:0000115 "Identifier of the immutable evidence snapshot."@en ;
oboInOwl:id "BEMO:3100029" .
bemo:BEMO_3100030 a owl:DatatypeProperty ;
rdfs:label "validation status text"@en ;
iao:0000115 "Human-readable validation status."@en ;
oboInOwl:id "BEMO:3100030" .
bemo:BEMO_3200001 a owl:AnnotationProperty ;
rdfs:label "source scientific definition"@en ;
iao:0000115 "Preserves the exact scientific definition from the source catalog."@en ;
oboInOwl:id "BEMO:3200001" .
bemo:BEMO_3200002 a owl:AnnotationProperty ;
rdfs:label "what it measures"@en ;
iao:0000115 "Preserves the source explanation of what a metric measures."@en ;
oboInOwl:id "BEMO:3200002" .
bemo:BEMO_3200003 a owl:AnnotationProperty ;
rdfs:label "why it matters"@en ;
iao:0000115 "Preserves the source rationale."@en ;
oboInOwl:id "BEMO:3200003" .
bemo:BEMO_3200004 a owl:AnnotationProperty ;
rdfs:label "measurement criteria"@en ;
iao:0000115 "Preserves the source measurement criteria."@en ;
oboInOwl:id "BEMO:3200004" .
bemo:BEMO_3200005 a owl:AnnotationProperty ;
rdfs:label "methods of assessment"@en ;
iao:0000115 "Preserves the source methods of assessment."@en ;
oboInOwl:id "BEMO:3200005" .
bemo:BEMO_3200006 a owl:AnnotationProperty ;
rdfs:label "common misinterpretations"@en ;
iao:0000115 "Preserves the source warnings about misinterpretation."@en ;
oboInOwl:id "BEMO:3200006" .
bemo:BEMO_3200007 a owl:AnnotationProperty ;
rdfs:label "limitations"@en ;
iao:0000115 "Preserves the source limitations."@en ;
oboInOwl:id "BEMO:3200007" .
bemo:BEMO_3200008 a owl:AnnotationProperty ;
rdfs:label "source evidence level"@en ;
iao:0000115 "Preserves the source evidence-level scope."@en ;
oboInOwl:id "BEMO:3200008" .
bemo:BEMO_3200009 a owl:AnnotationProperty ;
rdfs:label "source study types"@en ;
iao:0000115 "Preserves the source applicable study types."@en ;
oboInOwl:id "BEMO:3200009" .
bemo:BEMO_3200010 a owl:AnnotationProperty ;
rdfs:label "source frameworks"@en ;
iao:0000115 "Preserves the source related frameworks."@en ;
oboInOwl:id "BEMO:3200010" .
bemo:BEMO_3200011 a owl:AnnotationProperty ;
rdfs:label "source references"@en ;
iao:0000115 "Preserves the source reference list."@en ;
oboInOwl:id "BEMO:3200011" .
bemo:BEMO_3200012 a owl:AnnotationProperty ;
rdfs:label "computation profile IRI"@en ;
iao:0000115 "Links a metric class to its profile using an annotation-safe IRI."@en ;
oboInOwl:id "BEMO:3200012" .
bemo:BEMO_3200013 a owl:AnnotationProperty ;
rdfs:label "closely related metric"@en ;
iao:0000115 "Source-declared closely related metric."@en ;
oboInOwl:id "BEMO:3200013" .
bemo:BEMO_3200014 a owl:AnnotationProperty ;
rdfs:label "source workbook"@en ;
iao:0000115 "Name of the source workbook."@en ;
oboInOwl:id "BEMO:3200014" .
bemo:BEMO_3200015 a owl:AnnotationProperty ;
rdfs:label "source sheet"@en ;
iao:0000115 "Name of the source worksheet."@en ;
oboInOwl:id "BEMO:3200015" .
bemo:BEMO_3200016 a owl:AnnotationProperty ;
rdfs:label "lifecycle status"@en ;
iao:0000115 "Term lifecycle status."@en ;
oboInOwl:id "BEMO:3200016" .
bemo:BEMO_3200017 a owl:AnnotationProperty ;
rdfs:label "license status"@en ;
iao:0000115 "License status of the record or ontology."@en ;
oboInOwl:id "BEMO:3200017" .
bemo:BEMO_3200018 a owl:AnnotationProperty ;
rdfs:label "editor note"@en ;
iao:0000115 "Ontology-editor note."@en ;
oboInOwl:id "BEMO:3200018" .
bemo:BEMO_3200019 a owl:AnnotationProperty ;
rdfs:label "frequency of use"@en ;
iao:0000115 "Source-provided frequency-of-use classification."@en ;
oboInOwl:id "BEMO:3200019" .
bemo:BEMO_3200020 a owl:AnnotationProperty ;
rdfs:label "maturity of metric"@en ;
iao:0000115 "Source-provided maturity classification."@en ;
oboInOwl:id "BEMO:3200020" .
bemo:BEMO_4000023 a owl:NamedIndividual,
bemo:BEMO_0000402 ;
rdfs:label "Candidate"@en ;
iao:0000115 "Controlled BEMO LifecycleStatus value: Candidate."@en ;
oboInOwl:id "BEMO:4000023" ;
skos:notation "Candidate" .
bemo:BEMO_4000024 a owl:NamedIndividual,
bemo:BEMO_0000402 ;
rdfs:label "Stable"@en ;
iao:0000115 "Controlled BEMO LifecycleStatus value: Stable."@en ;
oboInOwl:id "BEMO:4000024" ;
skos:notation "Stable" .
bemo:BEMO_4000025 a owl:NamedIndividual,
bemo:BEMO_0000402 ;
rdfs:label "Deprecated"@en ;
iao:0000115 "Controlled BEMO LifecycleStatus value: Deprecated."@en ;
oboInOwl:id "BEMO:4000025" ;
skos:notation "Deprecated" .
bemo:BEMO_4000026 a owl:NamedIndividual,
bemo:BEMO_0000402 ;
rdfs:label "Obsolete"@en ;
iao:0000115 "Controlled BEMO LifecycleStatus value: Obsolete."@en ;
oboInOwl:id "BEMO:4000026" ;
skos:notation "Obsolete" .
bemo:BEMO_4000027 a owl:NamedIndividual,
bemo:BEMO_0000402 ;
rdfs:label "Draft"@en ;
iao:0000115 "Controlled BEMO ApprovalStatus value: Draft."@en ;
oboInOwl:id "BEMO:4000027" ;
skos:notation "Draft" .
bemo:BEMO_4000028 a owl:NamedIndividual,
bemo:BEMO_0000402 ;
rdfs:label "Under Review"@en ;
iao:0000115 "Controlled BEMO ApprovalStatus value: UnderReview."@en ;
oboInOwl:id "BEMO:4000028" ;
skos:notation "UnderReview" .
bemo:BEMO_4000029 a owl:NamedIndividual,
bemo:BEMO_0000402 ;
rdfs:label "Approved"@en ;
iao:0000115 "Controlled BEMO ApprovalStatus value: Approved."@en ;
oboInOwl:id "BEMO:4000029" ;
skos:notation "Approved" .
bemo:BEMO_4000030 a owl:NamedIndividual,
bemo:BEMO_0000402 ;
rdfs:label "Rejected"@en ;
iao:0000115 "Controlled BEMO ApprovalStatus value: Rejected."@en ;
oboInOwl:id "BEMO:4000030" ;
skos:notation "Rejected" .
a prov:Entity ;
dcterms:source obo:bfo.owl .
a prov:Entity ;
dcterms:source obo:eco.owl .
a prov:Entity ;
dcterms:source obo:obi.owl .
a prov:Entity ;
dcterms:source .
a owl:Ontology ;
dcterms:created "2026-08-02"^^xsd:date ;
dcterms:creator "BEMO Project" ;
dcterms:description "A provisional, computable ontology of pure biomedical evidence research metrics. Each source metric is represented as an OWL class and linked to a versioned computation specification."@en ;
dcterms:modified "2026-08-02"^^xsd:date ;
dcterms:source "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
dcterms:title "Biomedical Evidence Metrics Ontology (BEMO)"@en ;
rdfs:comment "DRAFT. This namespace is provisional, the ontology has not been reviewed or accepted by the OBO Foundry, and the final open license requires owner approval."@en ;
owl:imports obo:bfo.owl,
obo:eco.owl,
obo:iao.owl,
obo:obi.owl,
obo:ro.owl,
;
owl:versionIRI ;
owl:versionInfo "0.1.0" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO Foundry compatibility." .
bemo:BEMO_0000201 a owl:Class ;
rdfs:label "evidence object"@en ;
iao:0000115 "An entity or information artifact evaluated by a biomedical evidence metric, such as a claim, study, dataset, result, hypothesis, assay, or body of evidence."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000201" ;
rdfs:subClassOf iao:0000030 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_1000001 a owl:Class ;
rdfs:label "Evidence Synthesis and Certainty metric"@en ;
iao:0000115 "Metrics assessing the completeness, certainty, consistency, precision, and synthesis of biomedical evidence."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:1000001" ;
rdfs:subClassOf bemo:BEMO_0000001 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_1000008 a owl:Class ;
rdfs:label "Pharmacology and Toxicology metric"@en ;
iao:0000115 "Metrics assessing pharmacologic activity, exposure, efficacy, selectivity, and toxicologic evidence."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:1000008" ;
rdfs:subClassOf bemo:BEMO_0000001 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000200 a owl:Class ;
rdfs:label "metric assessment"@en ;
iao:0000115 "A measurement datum or structured assessment produced by applying a biomedical evidence metric to a defined evidence object using a specified computation profile."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000200" ;
rdfs:subClassOf iao:0000109 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_0000404 a owl:Class ;
rdfs:label "directionality"@en ;
iao:0000115 "A controlled concept describing how greater or lower values should be interpreted."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:0000404" ;
rdfs:subClassOf skos:Concept ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_1000003 a owl:Class ;
rdfs:label "Measurement, Assay, and Biospecimen Quality metric"@en ;
iao:0000115 "Metrics assessing analytical measurement performance, assay validity, biospecimen handling, and preanalytical quality."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:1000003" ;
rdfs:subClassOf bemo:BEMO_0000001 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_1000004 a owl:Class ;
rdfs:label "Reproducibility, Replication, and Research Transparency metric"@en ;
iao:0000115 "Metrics assessing reproducibility, independent replication, reporting completeness, and research transparency."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:1000004" ;
rdfs:subClassOf bemo:BEMO_0000001 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_1000006 a owl:Class ;
rdfs:label "Biological Mechanism and Experimental Evidence metric"@en ;
iao:0000115 "Metrics assessing biological plausibility, mechanistic evidence, experimental biology, and model-system evidence."@en ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:1000006" ;
rdfs:subClassOf bemo:BEMO_0000001 ;
bemo:BEMO_3200016 "Candidate" .
bemo:BEMO_2000002 a owl:Class ;
rdfs:label "Biological Plausibility"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of biological plausibility."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000002" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100001 ;
bemo:BEMO_3100001 "BEMO:2000002" ;
bemo:BEMO_3100022 9 ;
bemo:BEMO_3100023 "6cbc5f525d668cebb0928b8428848a625103a7b6492d0a2a618adb116f200bd3" ;
bemo:BEMO_3100024 9 ;
bemo:BEMO_3200002 "Assesses biological plausibility using evidence appropriate to biological plausibility and mechanism, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in biological plausibility can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified operational definition; appropriate comparator or reference; quantified uncertainty; independent or orthogonal corroboration; sensitivity analyses."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating biological plausibility as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Molecular, cellular, animal, translational, pharmacologic, and human studies"@en ;
bemo:BEMO_3200010 "GRADE; FDA Biomarker; ClinGen; OHAT; OECD"@en ;
bemo:BEMO_3200011 "https://www.gradeworkinggroup.org/ | https://www.fda.gov/media/119271/download | https://clinicalgenome.org/curation-activities/gene-disease-validity/ | https://ntp.niehs.nih.gov/whatwestudy/assessments/noncancer/handbook | https://www.oecd.org/chemicalsafety/testing/oecd-guidelines-testing-chemicals-related-documents.htm" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000012,
bemo:BEMO_2000014 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Established" .
bemo:BEMO_2000034 a owl:Class ;
rdfs:label "Clinical Validity"@en ;
iao:0000115 "The degree to which clinical supports the intended scientific interpretation without material systematic error."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000034" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100002 ;
bemo:BEMO_3100001 "BEMO:2000034" ;
bemo:BEMO_3100022 41 ;
bemo:BEMO_3100023 "628005d99d3e18a7b100ce400c64fc5218e46beeaa2cfec80dbac2445270cead" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses clinical validity using evidence appropriate to biomarker and endpoint validation, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in clinical validity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Clear intended use or estimand; accepted reference or criterion; prespecified acceptance thresholds; independent validation; performance across relevant conditions."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating clinical validity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Biomarker development, qualification, endpoint and surrogate validation studies"@en ;
bemo:BEMO_3200010 "FDA Biomarker; BEST; EMA E16; REMARK"@en ;
bemo:BEMO_3200011 "https://www.fda.gov/media/119271/download | https://www.ncbi.nlm.nih.gov/books/NBK326791/ | https://www.ema.europa.eu/en/ich-e16-genomic-biomarkers-related-drug-response-context-structure-format-qualification-submissions-scientific-guideline | https://www.equator-network.org/reporting-guidelines/reporting-recommendations-for-tumor-marker-prognostic-studies-remark/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000028,
bemo:BEMO_2000033 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Common within specialty" ;
bemo:BEMO_3200020 "Mature" .
bemo:BEMO_2000059 a owl:Class ;
rdfs:label "Biospecimen Integrity"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of biospecimen integrity."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000059" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100003 ;
bemo:BEMO_3100001 "BEMO:2000059" ;
bemo:BEMO_3100022 66 ;
bemo:BEMO_3100023 "b89a21b15f8ca110af0a2e2a28ae4ce7939819f7d62769c459c1cd5dc9b712cc" ;
bemo:BEMO_3100024 8 ;
bemo:BEMO_3200002 "Assesses biospecimen integrity using evidence appropriate to biospecimen and preanalytical quality, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in biospecimen integrity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified operational definition; appropriate comparator or reference; quantified uncertainty; independent or orthogonal corroboration; sensitivity analyses."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating biospecimen integrity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Specimen / assay / run / laboratory / study"@en ;
bemo:BEMO_3200009 "All studies using human or animal biospecimens"@en ;
bemo:BEMO_3200010 "BRISQ; ISO 15189; REMARK"@en ;
bemo:BEMO_3200011 "https://www.equator-network.org/reporting-guidelines/brisq/ | https://www.iso.org/standard/76677.html | https://www.equator-network.org/reporting-guidelines/reporting-recommendations-for-tumor-marker-prognostic-studies-remark/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000060,
bemo:BEMO_2000064 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Established" .
bemo:BEMO_2000086 a owl:Class ;
rdfs:label "Causal Identifiability"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of causal identifiability."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000086" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100004 ;
bemo:BEMO_3100001 "BEMO:2000086" ;
bemo:BEMO_3100022 93 ;
bemo:BEMO_3100023 "a6559bfe5ff78dd7455ed538b35cec6508c7c5507441bc614a71e2140188258e" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses causal identifiability using evidence appropriate to causal inference, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in causal identifiability can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified operational definition; appropriate comparator or reference; quantified uncertainty; independent or orthogonal corroboration; sensitivity analyses."@en ;
bemo:BEMO_3200005 "Directed acyclic graphs; design emulation; balance diagnostics; negative controls; quantitative bias analysis; sensitivity and falsification analyses."@en ;
bemo:BEMO_3200006 "Treating causal identifiability as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Randomized and observational etiologic studies, natural experiments, target-trial emulations"@en ;
bemo:BEMO_3200010 "ROBINS-I; ROBINS-E; GRADE; STROBE; ICH E9"@en ;
bemo:BEMO_3200011 "https://www.riskofbias.info/welcome/home/current-version-of-robins-i | https://www.riskofbias.info/welcome/robins-e-tool | https://www.gradeworkinggroup.org/ | https://www.equator-network.org/reporting-guidelines/strobe/ | https://database.ich.org/sites/default/files/E9_Guideline.pdf" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000088,
bemo:BEMO_2000104 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Established" .
bemo:BEMO_2000116 a owl:Class ;
rdfs:label "Diagnostic Sensitivity"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of diagnostic sensitivity."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000116" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100005 ;
bemo:BEMO_3100001 "BEMO:2000116" ;
bemo:BEMO_3100022 123 ;
bemo:BEMO_3100023 "4ea75714eea731a1e4644a00db0476f8628bf028934f92bd9e4029ee31ddf173" ;
bemo:BEMO_3100024 9 ;
bemo:BEMO_3200002 "Assesses diagnostic sensitivity using evidence appropriate to diagnostic and prognostic evidence, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in diagnostic sensitivity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified threshold; valid reference standard; complete 2×2 classification; confidence intervals; spectrum and prevalence assessment."@en ;
bemo:BEMO_3200005 "Two-by-two tables; binomial confidence intervals; hierarchical diagnostic meta-analysis; threshold and prevalence analyses."@en ;
bemo:BEMO_3200006 "Treating diagnostic sensitivity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Diagnostic accuracy, screening, prognostic-factor, and prediction-model studies"@en ;
bemo:BEMO_3200010 "QUADAS-2; STARD; TRIPOD; REMARK"@en ;
bemo:BEMO_3200011 "https://pubmed.ncbi.nlm.nih.gov/22007046/ | https://www.equator-network.org/reporting-guidelines/stard/ | https://www.tripod-statement.org/ | https://www.equator-network.org/reporting-guidelines/reporting-recommendations-for-tumor-marker-prognostic-studies-remark/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000117,
bemo:BEMO_2000128 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Common within specialty" ;
bemo:BEMO_3200020 "Mature" .
bemo:BEMO_2000160 a owl:Class ;
rdfs:label "Overall Evidence Certainty"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of overall evidence certainty."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000160" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100006 ;
bemo:BEMO_3100001 "BEMO:2000160" ;
bemo:BEMO_3100022 167 ;
bemo:BEMO_3100023 "31b48110148a1ebdd1379016bfff93898087ec61573fac3b850ccada3e1f7ae5" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses overall evidence certainty using evidence appropriate to evidence certainty and synthesis, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in overall evidence certainty can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified operational definition; appropriate comparator or reference; quantified uncertainty; independent or orthogonal corroboration; sensitivity analyses."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating overall evidence certainty as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Body of evidence / synthesis / outcome"@en ;
bemo:BEMO_3200009 "Systematic reviews, meta-analyses, evidence profiles, guidelines"@en ;
bemo:BEMO_3200010 "GRADE; PRISMA; AMSTAR 2; RoB"@en ;
bemo:BEMO_3200011 "https://www.gradeworkinggroup.org/ | https://www.prisma-statement.org/prisma-2020-checklist | https://www.bmj.com/content/358/bmj.j4008 | https://www.riskofbias.info/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000151,
bemo:BEMO_2000154 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Common" ;
bemo:BEMO_3200020 "Established" .
bemo:BEMO_2000176 a owl:Class ;
rdfs:label "Experimental Unit Validity"@en ;
iao:0000115 "The degree to which experimental unit supports the intended scientific interpretation without material systematic error."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000176" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100007 ;
bemo:BEMO_3100001 "BEMO:2000176" ;
bemo:BEMO_3100022 183 ;
bemo:BEMO_3100023 "3d08eaaab51eb4d1095b9fb5e884110ba36de86e61615acc1661c581f985a6b1" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses experimental unit validity using evidence appropriate to experimental biology and animal research, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in experimental unit validity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Clear intended use or estimand; accepted reference or criterion; prespecified acceptance thresholds; independent validation; performance across relevant conditions."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating experimental unit validity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "In vitro, ex vivo, organoid, animal, and preclinical experiments"@en ;
bemo:BEMO_3200010 "ARRIVE 2.0; SYRCLE; OECD"@en ;
bemo:BEMO_3200011 "https://arriveguidelines.org/arrive-guidelines | https://www.radboudumc.nl/en/research/departments/health-evidence/systematic-review-center-for-laboratory-animal-experimentation | https://www.oecd.org/chemicalsafety/testing/oecd-guidelines-testing-chemicals-related-documents.htm" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000171,
bemo:BEMO_2000189 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Mature" .
bemo:BEMO_2000197 a owl:Class ;
rdfs:label "External Validity"@en ;
iao:0000115 "The degree to which external supports the intended scientific interpretation without material systematic error."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000197" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100008 ;
bemo:BEMO_3100001 "BEMO:2000197" ;
bemo:BEMO_3100022 204 ;
bemo:BEMO_3100023 "291600cbcf719af0c4e82629e00cccabf1b55b19eff672c1fb6c5c7fe2ec4338" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses external validity using evidence appropriate to external validity and applicability, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in external validity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Clear intended use or estimand; accepted reference or criterion; prespecified acceptance thresholds; independent validation; performance across relevant conditions."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating external validity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Body of evidence / synthesis / outcome"@en ;
bemo:BEMO_3200009 "Clinical, epidemiologic, diagnostic, translational, and population studies"@en ;
bemo:BEMO_3200010 "GRADE; QUADAS-2; CONSORT; STROBE"@en ;
bemo:BEMO_3200011 "https://www.gradeworkinggroup.org/ | https://pubmed.ncbi.nlm.nih.gov/22007046/ | https://www.consort-spirit.org/ | https://www.equator-network.org/reporting-guidelines/strobe/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000203,
bemo:BEMO_2000205 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Mature" .
bemo:BEMO_2000221 a owl:Class ;
rdfs:label "Gene–Disease Validity"@en ;
iao:0000115 "The degree to which gene–disease supports the intended scientific interpretation without material systematic error."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000221" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100009 ;
bemo:BEMO_3100001 "BEMO:2000221" ;
bemo:BEMO_3100022 228 ;
bemo:BEMO_3100023 "4501a0d637c0d3d7b3852d3be8f61115b2b1ac442582dd9a3ec88bd21dad9f7c" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses gene–disease validity using evidence appropriate to genetics and variant evidence, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in gene–disease validity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Clear intended use or estimand; accepted reference or criterion; prespecified acceptance thresholds; independent validation; performance across relevant conditions."@en ;
bemo:BEMO_3200005 "ClinGen/ACMG evidence scoring; pedigree analysis; population databases; case-control data; functional assays; expert-panel review."@en ;
bemo:BEMO_3200006 "Treating gene–disease validity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Mendelian disease, cancer genetics, association, segregation, and functional studies"@en ;
bemo:BEMO_3200010 "ClinGen; ACMG AMP; STREGA; Gene Ontology"@en ;
bemo:BEMO_3200011 "https://clinicalgenome.org/curation-activities/gene-disease-validity/ | https://pubmed.ncbi.nlm.nih.gov/25741868/ | https://www.equator-network.org/reporting-guidelines/strega/ | https://geneontology.org/docs/guide-go-evidence-codes/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000230,
bemo:BEMO_2000235 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Mature" .
bemo:BEMO_2000257 a owl:Class ;
rdfs:label "Sequencing Depth Adequacy"@en ;
iao:0000115 "The extent to which sequencing depth is sufficient and fit for the stated biomedical inference."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000257" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100010 ;
bemo:BEMO_3100001 "BEMO:2000257" ;
bemo:BEMO_3100022 264 ;
bemo:BEMO_3100023 "719d5f0d3157f75114503dd8e8b0e75aa481929ab009d6c25b68024c7b5f71a0" ;
bemo:BEMO_3100024 8 ;
bemo:BEMO_3200002 "Assesses sequencing depth adequacy using evidence appropriate to genomics and transcriptomics, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in sequencing depth adequacy can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Clear intended use or estimand; accepted reference or criterion; prespecified acceptance thresholds; independent validation; performance across relevant conditions."@en ;
bemo:BEMO_3200005 "Read- and variant-level quality-control summaries; replicate concordance; orthogonal confirmation; benchmarking against reference materials."@en ;
bemo:BEMO_3200006 "Treating sequencing depth adequacy as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Whole-genome, exome, panel, bulk/single-cell/spatial transcriptomic studies"@en ;
bemo:BEMO_3200010 "MIAME; MINSEQE; STROBE-ME; GA4GH; HCA"@en ;
bemo:BEMO_3200011 "https://www.fged.org/projects/miame | https://www.fged.org/projects/minseqe/ | https://www.equator-network.org/reporting-guidelines/strobe-me/ | https://www.ga4gh.org/ | https://www.humancellatlas.org/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000246,
bemo:BEMO_2000250 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Established" .
bemo:BEMO_2000272 a owl:Class ;
rdfs:label "Analytical Validity"@en ;
iao:0000115 "The degree to which analytical supports the intended scientific interpretation without material systematic error."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000272" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100011 ;
bemo:BEMO_3100001 "BEMO:2000272" ;
bemo:BEMO_3100022 279 ;
bemo:BEMO_3100023 "e4b1deae92fd2c549054f6f19f234dbf0b73ab8ff30ff5741db1c88b5618f6c3" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses analytical validity using evidence appropriate to measurement and assay analytical validity, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in analytical validity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Clear intended use or estimand; accepted reference or criterion; prespecified acceptance thresholds; independent validation; performance across relevant conditions."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating analytical validity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Specimen / assay / run / laboratory / study"@en ;
bemo:BEMO_3200009 "Laboratory-developed tests, molecular assays, imaging, pathology, biomarker studies"@en ;
bemo:BEMO_3200010 "FDA Biomarker; CLSI; ISO 15189; MIQE"@en ;
bemo:BEMO_3200011 "https://www.fda.gov/media/119271/download | https://clsi.org/standards/products/method-evaluation/ | https://www.iso.org/standard/76677.html | https://pubmed.ncbi.nlm.nih.gov/19246619/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000267,
bemo:BEMO_2000302 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Common within specialty" ;
bemo:BEMO_3200020 "Mature" .
bemo:BEMO_2000304 a owl:Class ;
rdfs:label "Cross-Omics Integration Coherence"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of cross-omics integration coherence."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000304" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100012 ;
bemo:BEMO_3100001 "BEMO:2000304" ;
bemo:BEMO_3100022 311 ;
bemo:BEMO_3100023 "c10b406fc4ce6db5663280fc4b358cc062cc17f0ce7a593af68a762307815cdc" ;
bemo:BEMO_3100024 8 ;
bemo:BEMO_3200002 "Assesses cross-omics integration coherence using evidence appropriate to multi-omics and systems biology, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in cross-omics integration coherence can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified operational definition; appropriate comparator or reference; quantified uncertainty; independent or orthogonal corroboration; sensitivity analyses."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating cross-omics integration coherence as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Dataset / model / pathway / network / evidence body"@en ;
bemo:BEMO_3200009 "Integrated omics, networks, pathways, mechanistic and dynamic systems models"@en ;
bemo:BEMO_3200010 "Gene Ontology; Reactome; UniProt; GA4GH"@en ;
bemo:BEMO_3200011 "https://geneontology.org/docs/guide-go-evidence-codes/ | https://reactome.org/ | https://www.uniprot.org/help/evidences | https://www.ga4gh.org/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000303,
bemo:BEMO_2000305 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Developing" .
bemo:BEMO_2000348 a owl:Class ;
rdfs:label "Pharmacological Target Validity"@en ;
iao:0000115 "The degree to which pharmacological target supports the intended scientific interpretation without material systematic error."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000348" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100013 ;
bemo:BEMO_3100001 "BEMO:2000348" ;
bemo:BEMO_3100022 355 ;
bemo:BEMO_3100023 "2cff4752043ea892788f37639d922b1a249d83c13dfedf581ad1a4ad12ab95b8" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses pharmacological target validity using evidence appropriate to pharmacology and toxicology, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in pharmacological target validity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Clear intended use or estimand; accepted reference or criterion; prespecified acceptance thresholds; independent validation; performance across relevant conditions."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating pharmacological target validity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Pharmacology, pharmacokinetics, toxicology, safety and mode-of-action studies"@en ;
bemo:BEMO_3200010 "OECD; OHAT; FDA Biomarker; EMA E16"@en ;
bemo:BEMO_3200011 "https://www.oecd.org/chemicalsafety/testing/oecd-guidelines-testing-chemicals-related-documents.htm | https://ntp.niehs.nih.gov/whatwestudy/assessments/noncancer/handbook | https://www.fda.gov/media/119271/download | https://www.ema.europa.eu/en/ich-e16-genomic-biomarkers-related-drug-response-context-structure-format-qualification-submissions-scientific-guideline" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000337,
bemo:BEMO_2000347 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Mature" .
bemo:BEMO_2000374 a owl:Class ;
rdfs:label "Peptide Identification Confidence"@en ;
iao:0000115 "The justified degree of certainty assigned to peptide identification given the quantity, quality, consistency, and limitations of supporting evidence."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000374" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100014 ;
bemo:BEMO_3100001 "BEMO:2000374" ;
bemo:BEMO_3100022 381 ;
bemo:BEMO_3100023 "7f78eede8aa05781dde3f12d7ea8111e1c0b552f5b722c402b0de5323e65b0ea" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses peptide identification confidence using evidence appropriate to proteomics and metabolomics, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in peptide identification confidence can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified operational definition; appropriate comparator or reference; quantified uncertainty; independent or orthogonal corroboration; sensitivity analyses."@en ;
bemo:BEMO_3200005 "Target-decoy analysis; spectral scoring; reference standards; replicate injections; retention-time and mass-error monitoring; orthogonal confirmation."@en ;
bemo:BEMO_3200006 "Treating peptide identification confidence as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Mass spectrometry, affinity proteomics, metabolomics, lipidomics studies"@en ;
bemo:BEMO_3200010 "MIAPE; HUPO PSI; Metabolomics Standards"@en ;
bemo:BEMO_3200011 "https://www.psidev.info/miape | https://www.psidev.info/ | https://www.metabolomics-msi.org/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000363,
bemo:BEMO_2000377 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Established" .
bemo:BEMO_2000394 a owl:Class ;
rdfs:label "Independent Replication Strength"@en ;
iao:0000115 "The magnitude and credibility of independent evidence supporting independent replication."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000394" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100015 ;
bemo:BEMO_3100001 "BEMO:2000394" ;
bemo:BEMO_3100022 401 ;
bemo:BEMO_3100023 "3837461a84fca58515b90e02475b1cf195c845c2cf4704aa9d0c7c2b412d9406" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses independent replication strength using evidence appropriate to reproducibility and replication, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in independent replication strength can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Independent repeats; between-run/site/analyst variability; concordance of effect direction and magnitude; predefined reproducibility thresholds."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating independent replication strength as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "All experimental, computational, clinical, and omics studies"@en ;
bemo:BEMO_3200010 "PRISMA; CONSORT; MIAME; MINSEQE; MIAPE; ARRIVE 2.0"@en ;
bemo:BEMO_3200011 "https://www.prisma-statement.org/prisma-2020-checklist | https://www.consort-spirit.org/ | https://www.fged.org/projects/miame | https://www.fged.org/projects/minseqe/ | https://www.psidev.info/miape | https://arriveguidelines.org/arrive-guidelines" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000389,
bemo:BEMO_2000392 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Mature" .
bemo:BEMO_2000426 a owl:Class ;
rdfs:label "Protocol Availability"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of protocol availability."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000426" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100016 ;
bemo:BEMO_3100001 "BEMO:2000426" ;
bemo:BEMO_3100022 433 ;
bemo:BEMO_3100023 "6e6dfc0138818017108063ab02fea9da669c25ffc36ec988048eb058c538f84a" ;
bemo:BEMO_3100024 8 ;
bemo:BEMO_3200002 "Assesses protocol availability using evidence appropriate to research transparency and reporting completeness, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in protocol availability can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Required elements present; traceable provenance; unambiguous definitions; accessible underlying data/materials; documented deviations."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating protocol availability as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Study report / dataset / evidence package"@en ;
bemo:BEMO_3200009 "All biomedical study reports and data releases"@en ;
bemo:BEMO_3200010 "EQUATOR; PRISMA; CONSORT; STROBE; STARD; TRIPOD; CARE; CHEERS"@en ;
bemo:BEMO_3200011 "https://www.equator-network.org/ | https://www.prisma-statement.org/prisma-2020-checklist | https://www.consort-spirit.org/ | https://www.equator-network.org/reporting-guidelines/strobe/ | https://www.equator-network.org/reporting-guidelines/stard/ | https://www.tripod-statement.org/ | https://www.care-statement.org/ | https://www.equator-network.org/reporting-guidelines/cheers/" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000423,
bemo:BEMO_2000425 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Established within specialty" ;
bemo:BEMO_3200020 "Established" .
bemo:BEMO_2000439 a owl:Class ;
rdfs:label "Effect Magnitude"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of effect magnitude."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000439" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100017 ;
bemo:BEMO_3100001 "BEMO:2000439" ;
bemo:BEMO_3100022 446 ;
bemo:BEMO_3100023 "e21896fd55cc8da1ecb273cc15de195832d87a4d4554d2b68b3a9ce060442d84" ;
bemo:BEMO_3100024 8 ;
bemo:BEMO_3200002 "Assesses effect magnitude using evidence appropriate to statistical validity and inference, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in effect magnitude can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified operational definition; appropriate comparator or reference; quantified uncertainty; independent or orthogonal corroboration; sensitivity analyses."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating effect magnitude as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "All quantitative biomedical studies"@en ;
bemo:BEMO_3200010 "CONSORT; STROBE; TRIPOD; REMARK; ICH E9"@en ;
bemo:BEMO_3200011 "https://www.consort-spirit.org/ | https://www.equator-network.org/reporting-guidelines/strobe/ | https://www.tripod-statement.org/ | https://www.equator-network.org/reporting-guidelines/reporting-recommendations-for-tumor-marker-prognostic-studies-remark/ | https://database.ich.org/sites/default/files/E9_Guideline.pdf" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000435,
bemo:BEMO_2000441 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Common" ;
bemo:BEMO_3200020 "Established" .
bemo:BEMO_2000485 a owl:Class ;
rdfs:label "Randomization Integrity"@en ;
iao:0000115 "A canonical biomedical evidence metric quantifying the scientific credibility, reliability, relevance, or interpretability of randomization integrity."@en ;
iao:0000119 ;
oboInOwl:hasOBONamespace "bemo" ;
oboInOwl:id "BEMO:2000485" ;
rdfs:subClassOf [ a owl:Restriction ;
owl:hasValue ;
owl:onProperty bemo:BEMO_3000001 ],
bemo:BEMO_1100018 ;
bemo:BEMO_3100001 "BEMO:2000485" ;
bemo:BEMO_3100022 492 ;
bemo:BEMO_3100023 "8438f239c984919f366a44747e2e32efd683c0e45e3f7af6c269801f1d6694c8" ;
bemo:BEMO_3100024 10 ;
bemo:BEMO_3200002 "Assesses randomization integrity using evidence appropriate to study design and internal validity, distinguishing random uncertainty from systematic error."@en ;
bemo:BEMO_3200003 "Material weakness in randomization integrity can change the direction, magnitude, certainty, or biological interpretation of the research conclusion."@en ;
bemo:BEMO_3200004 "Prespecified operational definition; appropriate comparator or reference; quantified uncertainty; independent or orthogonal corroboration; sensitivity analyses."@en ;
bemo:BEMO_3200005 "Structured critical appraisal; quantitative estimation with uncertainty; prespecified thresholds; independent replication; sensitivity and subgroup analyses."@en ;
bemo:BEMO_3200006 "Treating randomization integrity as interchangeable with overall study quality, or interpreting a favorable value as proof that all other bias and validity domains are satisfactory."@en ;
bemo:BEMO_3200007 "Depends on context, operational definition, thresholds, data quality, and evaluator judgment; it should not be used as a stand-alone summary score without domain-level evidence."@en ;
bemo:BEMO_3200008 "Result / experiment / study / body of evidence, as applicable"@en ;
bemo:BEMO_3200009 "Randomized trials, nonrandomized intervention studies, cohort, case-control, cross-sectional studies"@en ;
bemo:BEMO_3200010 "CONSORT; STROBE; RoB 2; ROBINS-I; ROBINS-E; NIH Quality Tools; JBI"@en ;
bemo:BEMO_3200011 "https://www.consort-spirit.org/ | https://www.equator-network.org/reporting-guidelines/strobe/ | https://www.riskofbias.info/welcome/rob-2-0-tool | https://www.riskofbias.info/welcome/home/current-version-of-robins-i | https://www.riskofbias.info/welcome/robins-e-tool | https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools | https://jbi.global/critical-appraisal-tools" ;
bemo:BEMO_3200012 ;
bemo:BEMO_3200013 bemo:BEMO_2000464,
bemo:BEMO_2000466 ;
bemo:BEMO_3200014 "Pure_Biomedical_Evidence_Research_Metrics_Part_2(3).xlsx" ;
bemo:BEMO_3200015 "Biomedical Evidence Metrics" ;
bemo:BEMO_3200016 "Candidate" ;
bemo:BEMO_3200017 "Pending owner approval; CC BY 4.0 recommended for OBO compatibility." ;
bemo:BEMO_3200018 "Source content preserved verbatim; computation metadata is a generated default and must be curated before normative use."@en ;
bemo:BEMO_3200019 "Common" ;
bemo:BEMO_3200020 "Mature" .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biological Gradient"@en ;
dcterms:subject bemo:BEMO_2000001 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biological Plausibility"@en ;
dcterms:subject bemo:BEMO_2000002 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Cell-Type Specificity"@en ;
dcterms:subject bemo:BEMO_2000003 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Cross-Species Biological Concordance"@en ;
dcterms:subject bemo:BEMO_2000004 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Epistasis Support"@en ;
dcterms:subject bemo:BEMO_2000005 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Gain-of-Function Validation"@en ;
dcterms:subject bemo:BEMO_2000006 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Homeostatic Compensation Assessment"@en ;
dcterms:subject bemo:BEMO_2000007 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Loss-of-Function Validation"@en ;
dcterms:subject bemo:BEMO_2000008 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Mechanistic Causality Strength"@en ;
dcterms:subject bemo:BEMO_2000009 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Mechanistic Coherence"@en ;
dcterms:subject bemo:BEMO_2000010 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Mechanistic Completeness"@en ;
dcterms:subject bemo:BEMO_2000011 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Mechanistic Coverage"@en ;
dcterms:subject bemo:BEMO_2000012 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Mechanistic Specificity"@en ;
dcterms:subject bemo:BEMO_2000013 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Mechanistic Support"@en ;
dcterms:subject bemo:BEMO_2000014 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Molecular-Phenotypic Concordance"@en ;
dcterms:subject bemo:BEMO_2000015 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Network Context Support"@en ;
dcterms:subject bemo:BEMO_2000016 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Off-Target Liability Evidence"@en ;
dcterms:subject bemo:BEMO_2000017 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for On-Target Specificity"@en ;
dcterms:subject bemo:BEMO_2000018 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Pathway-Level Support"@en ;
dcterms:subject bemo:BEMO_2000019 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Perturbational Validation"@en ;
dcterms:subject bemo:BEMO_2000020 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Phenotypic Concordance"@en ;
dcterms:subject bemo:BEMO_2000021 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Rescue Experiment Support"@en ;
dcterms:subject bemo:BEMO_2000022 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Spatial Biological Concordance"@en ;
dcterms:subject bemo:BEMO_2000023 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Systems-Level Emergence Support"@en ;
dcterms:subject bemo:BEMO_2000024 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Target Engagement Evidence"@en ;
dcterms:subject bemo:BEMO_2000025 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Temporal Biological Concordance"@en ;
dcterms:subject bemo:BEMO_2000026 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Tissue Specificity"@en ;
dcterms:subject bemo:BEMO_2000027 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biomarker Clinical Relevance"@en ;
dcterms:subject bemo:BEMO_2000028 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biomarker Qualification Strength"@en ;
dcterms:subject bemo:BEMO_2000029 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biomarker Reliability"@en ;
dcterms:subject bemo:BEMO_2000030 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biomarker Responsiveness"@en ;
dcterms:subject bemo:BEMO_2000031 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biomarker Sensitivity to Change"@en ;
dcterms:subject bemo:BEMO_2000032 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biomarker-Outcome Association Strength"@en ;
dcterms:subject bemo:BEMO_2000033 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Clinical Validity"@en ;
dcterms:subject bemo:BEMO_2000034 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Construct Validity"@en ;
dcterms:subject bemo:BEMO_2000035 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Content Validity"@en ;
dcterms:subject bemo:BEMO_2000036 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Context-of-Use Validity"@en ;
dcterms:subject bemo:BEMO_2000037 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Convergent Validity"@en ;
dcterms:subject bemo:BEMO_2000038 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Criterion Validity"@en ;
dcterms:subject bemo:BEMO_2000039 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Diagnostic Biomarker Validity"@en ;
dcterms:subject bemo:BEMO_2000040 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Discriminant Validity"@en ;
dcterms:subject bemo:BEMO_2000041 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Endpoint Reliability"@en ;
dcterms:subject bemo:BEMO_2000042 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Endpoint Responsiveness"@en ;
dcterms:subject bemo:BEMO_2000043 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Endpoint Validity"@en ;
dcterms:subject bemo:BEMO_2000044 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Individual-Level Surrogacy"@en ;
dcterms:subject bemo:BEMO_2000045 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Known-Groups Validity"@en ;
dcterms:subject bemo:BEMO_2000046 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Minimal Clinically Important Difference Validity"@en ;
dcterms:subject bemo:BEMO_2000047 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Monitoring Biomarker Validity"@en ;
dcterms:subject bemo:BEMO_2000048 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Outcome Relevance"@en ;
dcterms:subject bemo:BEMO_2000049 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Pharmacodynamic Biomarker Validity"@en ;
dcterms:subject bemo:BEMO_2000050 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Predictive Biomarker Validity"@en ;
dcterms:subject bemo:BEMO_2000051 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Prognostic Biomarker Validity"@en ;
dcterms:subject bemo:BEMO_2000052 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Response Biomarker Validity"@en ;
dcterms:subject bemo:BEMO_2000053 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Safety Biomarker Validity"@en ;
dcterms:subject bemo:BEMO_2000054 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Surrogate Endpoint Validity"@en ;
dcterms:subject bemo:BEMO_2000055 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Susceptibility/Risk Biomarker Validity"@en ;
dcterms:subject bemo:BEMO_2000056 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000006 ;
bemo:BEMO_3000008 bemo:BEMO_4000010 ;
bemo:BEMO_3000009 bemo:BEMO_4000015 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000022 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned risk rubric or calibrated probability model defined for the metric and context."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_risk_category\",\"probability\",\"percentage\"]}" ;
bemo:BEMO_3100006 "risk_factors; assessment_context; rubric_or_model_version; evidence_records" ;
bemo:BEMO_3100007 "weights; thresholds; calibration_dataset" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal risk rating or quantitative percentage/probability; lower is generally better" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for probability outputs; rubric reliability required for ordinal outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Trial-Level Surrogacy"@en ;
dcterms:subject bemo:BEMO_2000057 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Anatomical Site Fidelity"@en ;
dcterms:subject bemo:BEMO_2000058 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biospecimen Integrity"@en ;
dcterms:subject bemo:BEMO_2000059 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Biospecimen Provenance Completeness"@en ;
dcterms:subject bemo:BEMO_2000060 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Cellularity Adequacy"@en ;
dcterms:subject bemo:BEMO_2000061 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Chain-of-Custody Integrity"@en ;
dcterms:subject bemo:BEMO_2000062 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Cold Ischemia Control"@en ;
dcterms:subject bemo:BEMO_2000063 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Collection Procedure Consistency"@en ;
dcterms:subject bemo:BEMO_2000064 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for DNA Integrity"@en ;
dcterms:subject bemo:BEMO_2000065 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Fixation Adequacy"@en ;
dcterms:subject bemo:BEMO_2000066 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Freeze–Thaw Burden"@en ;
dcterms:subject bemo:BEMO_2000067 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000006 ;
bemo:BEMO_3000008 bemo:BEMO_4000010 ;
bemo:BEMO_3000009 bemo:BEMO_4000015 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000022 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned risk rubric or calibrated probability model defined for the metric and context."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_risk_category\",\"probability\",\"percentage\"]}" ;
bemo:BEMO_3100006 "risk_factors; assessment_context; rubric_or_model_version; evidence_records" ;
bemo:BEMO_3100007 "weights; thresholds; calibration_dataset" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal risk rating or quantitative percentage/probability; lower is generally better" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for probability outputs; rubric reliability required for ordinal outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Hemolysis Burden"@en ;
dcterms:subject bemo:BEMO_2000068 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000006 ;
bemo:BEMO_3000008 bemo:BEMO_4000010 ;
bemo:BEMO_3000009 bemo:BEMO_4000015 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000022 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned risk rubric or calibrated probability model defined for the metric and context."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_risk_category\",\"probability\",\"percentage\"]}" ;
bemo:BEMO_3100006 "risk_factors; assessment_context; rubric_or_model_version; evidence_records" ;
bemo:BEMO_3100007 "weights; thresholds; calibration_dataset" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal risk rating or quantitative percentage/probability; lower is generally better" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for probability outputs; rubric reliability required for ordinal outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Icterus Interference"@en ;
dcterms:subject bemo:BEMO_2000069 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Lipemia Burden"@en ;
dcterms:subject bemo:BEMO_2000070 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000006 ;
bemo:BEMO_3000008 bemo:BEMO_4000010 ;
bemo:BEMO_3000009 bemo:BEMO_4000015 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000022 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned risk rubric or calibrated probability model defined for the metric and context."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_risk_category\",\"probability\",\"percentage\"]}" ;
bemo:BEMO_3100006 "risk_factors; assessment_context; rubric_or_model_version; evidence_records" ;
bemo:BEMO_3100007 "weights; thresholds; calibration_dataset" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal risk rating or quantitative percentage/probability; lower is generally better" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for probability outputs; rubric reliability required for ordinal outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Matched-Sample Integrity"@en ;
dcterms:subject bemo:BEMO_2000071 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Microbial Contamination"@en ;
dcterms:subject bemo:BEMO_2000072 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000006 ;
bemo:BEMO_3000008 bemo:BEMO_4000010 ;
bemo:BEMO_3000009 bemo:BEMO_4000015 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000022 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned risk rubric or calibrated probability model defined for the metric and context."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_risk_category\",\"probability\",\"percentage\"]}" ;
bemo:BEMO_3100006 "risk_factors; assessment_context; rubric_or_model_version; evidence_records" ;
bemo:BEMO_3100007 "weights; thresholds; calibration_dataset" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal risk rating or quantitative percentage/probability; lower is generally better" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for probability outputs; rubric reliability required for ordinal outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Necrosis Burden"@en ;
dcterms:subject bemo:BEMO_2000073 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000006 ;
bemo:BEMO_3000008 bemo:BEMO_4000010 ;
bemo:BEMO_3000009 bemo:BEMO_4000015 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000022 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned risk rubric or calibrated probability model defined for the metric and context."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_risk_category\",\"probability\",\"percentage\"]}" ;
bemo:BEMO_3100006 "risk_factors; assessment_context; rubric_or_model_version; evidence_records" ;
bemo:BEMO_3100007 "weights; thresholds; calibration_dataset" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal risk rating or quantitative percentage/probability; lower is generally better" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for probability outputs; rubric reliability required for ordinal outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Pathology Confirmation"@en ;
dcterms:subject bemo:BEMO_2000074 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Preservation Adequacy"@en ;
dcterms:subject bemo:BEMO_2000075 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Processing Delay Control"@en ;
dcterms:subject bemo:BEMO_2000076 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Protein Integrity"@en ;
dcterms:subject bemo:BEMO_2000077 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for RNA Integrity"@en ;
dcterms:subject bemo:BEMO_2000078 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Storage Temperature Control"@en ;
dcterms:subject bemo:BEMO_2000079 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Time-to-Fixation Adequacy"@en ;
dcterms:subject bemo:BEMO_2000080 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Transport Condition Integrity"@en ;
dcterms:subject bemo:BEMO_2000081 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Tumor Purity"@en ;
dcterms:subject bemo:BEMO_2000082 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Warm Ischemia Control"@en ;
dcterms:subject bemo:BEMO_2000083 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Assumption Sensitivity"@en ;
dcterms:subject bemo:BEMO_2000084 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000004 ;
bemo:BEMO_3000008 bemo:BEMO_4000008 ;
bemo:BEMO_3000009 bemo:BEMO_4000017 ;
bemo:BEMO_3000010 bemo:BEMO_4000019 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "value = numerator / denominator, with denominator > 0"@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"divide\",\"arguments\":[\"numerator\",\"denominator\"],\"constraints\":[\"denominator > 0\"]}" ;
bemo:BEMO_3100006 "numerator; denominator; operational_definition; assessment_context" ;
bemo:BEMO_3100007 "weight; stratum; confidence_level" ;
bemo:BEMO_3100008 "xsd:decimal" ;
bemo:BEMO_3100009 "Proportion or percentage (0–1 or 0–100%)" ;
bemo:BEMO_3100010 0.0 ;
bemo:BEMO_3100011 1.0 ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; required when interpreted probabilistically."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Causal Contrast Clarity"@en ;
dcterms:subject bemo:BEMO_2000085 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Causal Identifiability"@en ;
dcterms:subject bemo:BEMO_2000086 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Collider Bias Risk"@en ;
dcterms:subject bemo:BEMO_2000087 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000006 ;
bemo:BEMO_3000008 bemo:BEMO_4000010 ;
bemo:BEMO_3000009 bemo:BEMO_4000015 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000022 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned risk rubric or calibrated probability model defined for the metric and context."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_risk_category\",\"probability\",\"percentage\"]}" ;
bemo:BEMO_3100006 "risk_factors; assessment_context; rubric_or_model_version; evidence_records" ;
bemo:BEMO_3100007 "weights; thresholds; calibration_dataset" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal risk rating or quantitative percentage/probability; lower is generally better" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for probability outputs; rubric reliability required for ordinal outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Mature; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Confounding Risk"@en ;
dcterms:subject bemo:BEMO_2000088 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000006 ;
bemo:BEMO_3000008 bemo:BEMO_4000010 ;
bemo:BEMO_3000009 bemo:BEMO_4000015 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000022 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned risk rubric or calibrated probability model defined for the metric and context."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_risk_category\",\"probability\",\"percentage\"]}" ;
bemo:BEMO_3100006 "risk_factors; assessment_context; rubric_or_model_version; evidence_records" ;
bemo:BEMO_3100007 "weights; thresholds; calibration_dataset" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal risk rating or quantitative percentage/probability; lower is generally better" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for probability outputs; rubric reliability required for ordinal outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Consistency Assumption Plausibility"@en ;
dcterms:subject bemo:BEMO_2000089 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Correct Temporal Ordering"@en ;
dcterms:subject bemo:BEMO_2000090 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000001 ;
bemo:BEMO_3000008 bemo:BEMO_4000007 ;
bemo:BEMO_3000009 bemo:BEMO_4000014 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned metric-specific computation protocol consistent with the source definition, criteria, and methods."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\"}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; operational_definition; computation_protocol_version" ;
bemo:BEMO_3100007 "weights; thresholds; reference_standard; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:anySimpleType" ;
bemo:BEMO_3100009 "Metric-specific continuous, categorical, or ordinal scale" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 true ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "As applicable; mandatory for probabilistic or normalized outputs."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Dechallenge–Rechallenge Support"@en ;
dcterms:subject bemo:BEMO_2000091 ;
prov:wasDerivedFrom ;
bemo:BEMO_3000007 bemo:BEMO_4000002 ;
bemo:BEMO_3000008 bemo:BEMO_4000011 ;
bemo:BEMO_3000009 bemo:BEMO_4000016 ;
bemo:BEMO_3000010 bemo:BEMO_4000018 ;
bemo:BEMO_3000011 bemo:BEMO_4000021 ;
bemo:BEMO_3100002 "0.1.0" ;
bemo:BEMO_3100003 "Apply a versioned, prespecified domain rubric or validated normalized scoring model."@en ;
bemo:BEMO_3100004 "BEMO-Expression-JSON" ;
bemo:BEMO_3100005 "{\"language\":\"BEMO-Expression-JSON\",\"operator\":\"external_protocol\",\"protocolRef\":\"REQUIRED\",\"allowed_outputs\":[\"ordinal_category\",\"normalized_score\"]}" ;
bemo:BEMO_3100006 "evidence_records; assessment_context; rubric_version; operational_definition" ;
bemo:BEMO_3100007 "weights; thresholds; expert_adjudication" ;
bemo:BEMO_3100008 "xsd:string_or_decimal" ;
bemo:BEMO_3100009 "Ordinal rubric, domain judgment, or normalized score" ;
bemo:BEMO_3100013 "Not specified in source; must be defined and versioned before composite use."@en ;
bemo:BEMO_3100014 "None by default; any normalization must be justified, versioned, and validated."@en ;
bemo:BEMO_3100015 "Must be declared before computation; report missingness; no silent imputation; perform sensitivity analysis when material."@en ;
bemo:BEMO_3100016 true ;
bemo:BEMO_3100017 "Confidence interval, credible interval, bootstrap distribution, inter-rater reliability, or sensitivity analysis as scientifically applicable."@en ;
bemo:BEMO_3100018 false ;
bemo:BEMO_3100019 "Prespecify, justify, version, and sensitivity-test thresholds; do not derive and evaluate on the same data without correction."@en ;
bemo:BEMO_3100020 "Source provenance; input validation; duplicate control; uncertainty reporting; independent or orthogonal validation where applicable."@en ;
bemo:BEMO_3100021 "Required for normalized scores; inter-rater reliability required for human rubrics."@en ;
bemo:BEMO_3100030 "Source maturity: Established; BEMO computation profile requires independent validation."@en .
a bemo:BEMO_0000100 ;
rdfs:label "Computation profile for Dose–Response Support"@en ;
dcterms:subject bemo:BEMO_2000092 ;
prov:wasDerivedFrom